Statistical Methods for Low-frequency and Rare Genetic Variants
نویسندگان
چکیده
................................................................................................................................................................... xi Chapter 1: Introduction ...................................................................................................................................... 1 Chapter 2: Recommended joint and meta-analysis strategies for case-control association testing of single low count variants ............................................................................................................... 7 Chapter 3: Near equivalent calibration and power of joint and meta-analysis for association analysis of quantitative traits ........................................................................................................................ 38 Chapter 4: Evaluating the calibration and power of three gene-based association tests for the X chromosome ............................................................................................................................................. 57 Chapter 5: Summary, discussion, and future directions ..................................................................... 79 References ............................................................................................................................................................ 84
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Rare and low-frequency variants in human common diseases and other complex traits.
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